Description

4-Amino-1,2-Dihydro-2-Methyl-3H-Pyrrolo[3,4-C]Pyridin-3-One is a high-purity, advanced pharmaceutical intermediate with a complex fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs. Its precise structure offers a strategic point for chemical modification, enabling the exploration of new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of targeted drug candidates, especially in oncology and neurology research.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Its pyrrolopyridine core is a privileged structure found in many kinase inhibitors, making it valuable for developing new therapeutics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.
• Bioconjugation & Probe Synthesis: The amino group provides a handle for conjugation, useful in creating chemical probes for biological assays.

Basic Information

Product Name	4-Amino-1,2-Dihydro-2-Methyl-3H-Pyrrolo[3,4-C]Pyridin-3-One
CAS No.	1257998-52-9
Molecular Formula	C8H9N3O
Molecular Weight	163.18 g/mol
Synonyms	4-Amino-2-methyl-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one; 2-Methyl-4-amino-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one; 4-Amino-2-methyl-1H-pyrrolo[3,4-c]pyridin-3(2H)-one; Pyrrolo[3,4-c]pyridin-3-one, 4-amino-1,2-dihydro-2-methyl-; CAS 1257998-52-9
EINECS	Contact for details

Quality Control

Our 4-Amino-1,2-Dihydro-2-Methyl-3H-Pyrrolo[3,4-C]Pyridin-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.