Description

(3-Fluoro-5-Methoxy-4-Nitrophenyl)Methanol is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a nitrophenyl core with strategically placed fluoro and methoxy substituents, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for fluorinated aromatic components in advanced electronic display and lighting materials.
• Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments where the nitro and methoxy groups contribute to color properties and solubility.
• Cross-Coupling Reactions: The functional groups present make it a suitable substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	(3-Fluoro-5-Methoxy-4-Nitrophenyl)Methanol
CAS No.	1257997-29-7
Molecular Formula	C8H8FNO4
Molecular Weight	201.15 g/mol
Synonyms	4-Nitro-3-fluoro-5-methoxybenzyl alcohol; (3-Fluoro-5-methoxy-4-nitrophenyl)methanol; 3-Fluoro-5-methoxy-4-nitrobenzenemethanol; 1-(3-Fluoro-5-methoxy-4-nitrophenyl)methanol; Benzyl alcohol, 3-fluoro-5-methoxy-4-nitro-
EINECS	Contact for details

Quality Control

Our (3-Fluoro-5-Methoxy-4-Nitrophenyl)Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.