Description

tert-Butyl 2-Chloro-5H-Pyrrolo[3,4-B]Pyridine-6(7H)-Carboxylate is a high-value, heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the synthesis of complex bioactive molecules, particularly in kinase inhibitor development. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Serves as a protected, functionalized intermediate for constructing complex fused heterocyclic systems.
• API Development: Employed in the research and process development stages for new active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Can be utilized to develop tool compounds for investigating biological pathways and target validation.

Basic Information

Product Name	tert-Butyl 2-Chloro-5H-Pyrrolo[3,4-B]Pyridine-6(7H)-Carboxylate
CAS No.	1257854-60-6
Molecular Formula	C12H13ClN2O2
Molecular Weight	252.70 g/mol
Synonyms	2-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-6-carboxylic acid tert-butyl ester; tert-Butyl 2-chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-6-carboxylate; 2-Chloro-5,6,7,8-tetrahydropyrrolo[3,4-b]pyridine-6-carboxylic acid tert-butyl ester; 2-Chloro-5H-pyrrolo[3,4-b]pyridine-6(7H)-carboxylic acid, 1,1-dimethylethyl ester; 1257854-60-6; tert-Butyl 2-chloro-5,6,7,8-tetrahydropyrrolo[3,4-b]pyridine-6-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chloro-5H-Pyrrolo[3,4-B]Pyridine-6(7H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full specifications are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.