Description

Ethyl 4,7-Dibromo-1,5-Naphthyridine-3-Carboxylate is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its role as a versatile precursor for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for their synthetic pipelines.

Application

This specialized naphthyridine derivative serves as a critical intermediate in several high-value research and development areas:

• Pharmaceutical Intermediate: A key building block for the synthesis of potential active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the creation of novel compounds for crop protection and pest management research programs.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized to create labeled or modified compounds for studying biological pathways and target engagement.
• Academic & Contract Research: A valuable reagent for methodology development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Scale-up & Process Chemistry: Serves as a starting material for optimizing synthetic routes during the scale-up phase of drug candidate development.

Basic Information

Product Name	Ethyl 4,7-Dibromo-1,5-Naphthyridine-3-Carboxylate
CAS No.	1257852-54-2
Molecular Formula	C11H8Br2N2O2
Molecular Weight	360.00 g/mol
Synonyms	1,5-Naphthyridine-3-carboxylic acid, 4,7-dibromo-, ethyl ester; Ethyl 4,7-dibromo-1,5-naphthyridine-3-carboxylate; 4,7-Dibromo-1,5-naphthyridine-3-carboxylic acid ethyl ester; 1,5-Naphthyridine-3-carboxylate, 4,7-dibromo-, ethyl ester; Ethyl 4,7-dibromonaphthyridine-3-carboxylate; CAS 1257852-54-2
EINECS	Contact for details

Quality Control

Our Ethyl 4,7-Dibromo-1,5-Naphthyridine-3-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project needs, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.