Description

3-Chloro-1,8A-Dihydroimidazo[1,2-A]Pyridine-8-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process R&D, and the synthesis of new chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules containing fused imidazopyridine scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new therapeutic avenues.
• Process Chemistry Development: Serves as a starting material or advanced intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Potential building block for creating novel crop protection agents and pesticides with specific biological activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic Research: Employed in universities and research institutes for methodological studies in heterocyclic chemistry and new reaction development.

Basic Information

Item	Details
Product Name	3-Chloro-1,8A-Dihydroimidazo[1,2-A]Pyridine-8-Carboxylic Acid
CAS No.	1257852-46-2
Molecular Formula	C8H7ClN2O2
Molecular Weight	198.61 g/mol
Synonyms	3-Chloro-1,8a-dihydroimidazo[1,2-a]pyridine-8-carboxylic acid; 1,8a-Dihydroimidazo[1,2-a]pyridine-8-carboxylic acid, 3-chloro-; 3-Chloroimidazo[1,2-a]pyridine-8-carboxylic acid (tautomeric form); 1257852-46-2; 3-Chloro-1,8a-dihydro-8H-imidazo[1,2-a]pyridine-8-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-1,8A-Dihydroimidazo[1,2-A]Pyridine-8-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.