Description

8-Bromo-6-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyridin-2-Ylamine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because it provides a unique trifluoromethylated triazolopyridine scaffold, offering significant potential for modulating the physicochemical and biological properties of target molecules. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl and bromo substituents can enhance bioactivity and environmental stability.
• Material Science Precursor: Acts as a specialized monomer or ligand precursor for creating advanced organic electronic materials or metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways due to its distinctive heterocyclic structure.
• Custom Synthesis & Scale-Up: A key starting material for contract research and manufacturing organizations (CROs/CMOs) engaged in custom synthesis projects requiring complex fluorinated heterocycles.

Basic Information

Product Name	8-Bromo-6-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyridin-2-Ylamine
CAS No.	1257705-46-6
Molecular Formula	C7H3BrF3N4
Molecular Weight	280.03 g/mol
Synonyms	8-Bromo-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 2-Amino-8-bromo-6-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridine; 8-Bromo-6-trifluoromethyl-1,2,4-triazolo[1,5-a]pyridin-2-ylamine; 1257705-46-6; 8-Bromo-6-(trifluoromethyl)-1,2,4-triazolo[1,5-a]pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyridin-2-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.