Description

(3-Bromo-5-Methylpyridin-2-Yl)Methanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to introduce specific bromo and amine functionalities into molecular frameworks.
• Agrochemical Synthesis: Serves as a precursor for developing novel pesticides, herbicides, and fungicides that require substituted pyridine cores.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Chemical Biology Probes: Useful for creating molecular probes to study enzyme function and biological pathways due to its reactive handles.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	(3-Bromo-5-Methylpyridin-2-Yl)Methanamine Hydrochloride
CAS No.	1257535-62-8
Molecular Formula	C7H10BrClN2
Molecular Weight	237.52 g/mol
Synonyms	2-(Aminomethyl)-3-bromo-5-methylpyridine hydrochloride; 1-(3-Bromo-5-methylpyridin-2-yl)methanamine hydrochloride; (3-Bromo-5-methyl-2-pyridinyl)methanamine hydrochloride; 2-Pyridinemethanamine, 3-bromo-5-methyl-, hydrochloride; 3-Bromo-5-methyl-2-pyridinemethanamine hydrochloride; (3-Bromo-5-methyl-pyridin-2-yl)-methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Bromo-5-Methylpyridin-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.