Description

n-Methyl-4-{[4-(Trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonamide CAS NO 1257535-25-3 is a high-purity, advanced pharmaceutical intermediate featuring a unique sulfonamide-pyridine hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in developing new therapeutic agents, especially in areas targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Agrochemical Development: Serves as a precursor in the research of new crop protection agents and herbicides.
• Biochemical Tool Compound: Utilized in biochemical assays to study specific protein-ligand interactions and enzyme functions.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, non-commercial chemical entities for client-specific projects.

Basic Information

Product Name	n-Methyl-4-{[4-(Trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonamide
CAS No.	1257535-25-3
Molecular Formula	C14H11F3N2O3S
Molecular Weight	344.31 g/mol
Synonyms	4-[(4-(Trifluoromethyl)pyridin-2-yl)oxy]-N-methylbenzenesulfonamide; N-Methyl-4-((4-(trifluoromethyl)pyridin-2-yl)oxy)benzenesulfonamide; 2-[(4-(Methylsulfamoyl)phenoxy]-4-(trifluoromethyl)pyridine; 1257535-25-3; Benzenesulfonamide, N-methyl-4-[[4-(trifluoromethyl)-2-pyridinyl]oxy]-; 4-{[4-(Trifluoromethyl)pyridin-2-yl]oxy}-N-methylbenzenesulfonamide
EINECS	Contact for details

Quality Control

Our n-Methyl-4-{[4-(Trifluoromethyl)pyridin-2-yl]oxy}benzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.