Description

(3-Fluoro-6-Methylpyridin-2-Yl)Methanamine Hydrochloride is a high-purity, organofluorine building block essential for advanced pharmaceutical and agrochemical research and development. Its value lies in its role as a key synthetic intermediate for introducing the unique physicochemical properties of fluorine into target molecules, potentially enhancing their metabolic stability, bioavailability, and binding affinity. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atom can improve efficacy and environmental profile.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Fluorinated Compound Libraries: Used in combinatorial chemistry and high-throughput screening to build diverse libraries of fluorinated compounds for discovery.

Basic Information

Product Name	(3-Fluoro-6-Methylpyridin-2-Yl)Methanamine Hydrochloride
CAS No.	1257535-11-7
Molecular Formula	C7H10ClFN2
Molecular Weight	176.62 g/mol
Synonyms	2-(Aminomethyl)-3-fluoro-6-methylpyridine hydrochloride; (3-Fluoro-6-methyl-2-pyridinyl)methanamine hydrochloride; 1-(3-Fluoro-6-methylpyridin-2-yl)methanamine hydrochloride; 2-Pyridinemethanamine, 3-fluoro-6-methyl-, hydrochloride; 3-Fluoro-6-methyl-2-pyridinemethanamine hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Fluoro-6-Methylpyridin-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.