Description

Tovok Bibw2992 CAS NO 1254955-21-9 is a high-purity, small molecule pharmaceutical intermediate and reference standard of significant importance in oncology research and development. This compound serves as a critical building block for the synthesis of advanced therapeutic agents targeting specific kinase pathways. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in the discovery and production of innovative cancer treatments.

Application

• As a key pharmaceutical intermediate in the synthesis of targeted oncology drugs.
• As a reference standard for analytical method development, validation, and quality control in API manufacturing.
• For preclinical research and biochemical assays studying kinase inhibition mechanisms.
• In process chemistry and scale-up studies within GMP production environments.
• As a starting material for the development of novel drug conjugates and prodrugs.
• For use in academic research programs focused on signal transduction and cancer biology.

Basic Information

Product Name	Tovok Bibw2992
CAS No.	1254955-21-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BIBW 2992; Tovok; Afatinib Impurity; Afatinib Intermediate; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6- quinazolinyl]-4-(dimethylamino)-2-butenamide; Tovok (BIBW2992); BIBW-2992
EINECS	Contact for details

Quality Control

Our Tovok Bibw2992 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.