Description

Methyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the naphthyridine class of heterocyclic compounds. Its value lies in its role as a critical building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex molecules in medicinal and combinatorial chemistry.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for exploratory research and method development.
• Process Chemistry Development: Used for optimizing synthetic routes and scaling up production of target molecules in pilot plants.

Basic Information

Product Name	Methyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate
CAS No.	1253888-80-0
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	Methyl 5,6,7,8-tetrahydro-1,7-naphthyridine-3-carboxylate; 1,7-Naphthyridine-3-carboxylic acid, 5,6,7,8-tetrahydro-, methyl ester; Methyl 5,6,7,8-tetrahydro[1,7]naphthyridine-3-carboxylate; 3-(Methoxycarbonyl)-5,6,7,8-tetrahydro-1,7-naphthyridine
EINECS	Contact for details

Quality Control

Our production of Methyl 5,6,7,8-Tetrahydro-1,7-Naphthyridine-3-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.