Description

4-(Trifluoromethyl)Pyridine-2-Sulfonic Acid Amide is a high-value, multi-functional heterocyclic building block featuring a sulfonamide group and a trifluoromethyl substituent. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique structure imparts desirable metabolic stability and bioavailability. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for use in medicinal chemistry and as a key synthetic intermediate.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging the bioactivity of the pyridine-sulfonamide core.
• Material Science Research: Serves as a precursor for functional ligands or monomers in the creation of advanced polymers and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring the introduction of a trifluoromethylated pyridine-sulfonamide moiety.

Basic Information

Product Name	4-(Trifluoromethyl)Pyridine-2-Sulfonic Acid Amide
CAS No.	1252046-10-8
Molecular Formula	C7H5F3N2O2S
Molecular Weight	238.19 g/mol
Synonyms	2-Pyridinesulfonamide, 4-(trifluoromethyl)-; 4-(Trifluoromethyl)pyridine-2-sulfonamide; 4-Trifluoromethylpyridine-2-sulfonic acid amide; 2-Sulfamoyl-4-(trifluoromethyl)pyridine; 4-(Trifluoromethyl)-2-pyridinesulfonamide; 4-CF3-Pyridine-2-sulfonamide
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Pyridine-2-Sulfonic Acid Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.