Description

(6-Bromopyridin-3-Yl)Methanamine Dihydrochloride is a high-purity, versatile brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a reactive handle for cross-coupling reactions and further functionalization, enabling the rapid construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: A monomer or functional unit in the development of organic electronic materials, such as conductive polymers and OLED components.
• Cross-Coupling Reactions: The bromine atom is an excellent site for Suzuki, Stille, and Buchwald-Hartwig amination reactions to introduce diverse aryl and heteroaryl groups.

Basic Information

Product Name	(6-Bromopyridin-3-Yl)Methanamine Dihydrochloride
CAS No.	1251953-04-4
Molecular Formula	C6H8BrCl2N2
Molecular Weight	268.95 g/mol
Synonyms	1-(6-Bromopyridin-3-yl)methanamine dihydrochloride; (6-Bromo-3-pyridyl)methanamine dihydrochloride; 5-(Aminomethyl)-2-bromopyridine dihydrochloride; 2-Bromo-5-(aminomethyl)pyridine dihydrochloride; 6-Bromo-3-pyridinemethanamine dihydrochloride; 3-Pyridinemethanamine, 6-bromo-, dihydrochloride
EINECS	Contact for details

Quality Control

Our (6-Bromopyridin-3-Yl)Methanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.