Description

(5-Bromopyridin-2-Yl)Methanamine Dihydrochloride is a high-purity, versatile pyridine-based building block essential for advanced organic synthesis. Its primary value lies in its functionalized structure, which serves as a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is particularly sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the bromo and amine functionalities for structural diversification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of novel polymers and advanced organic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	(5-Bromopyridin-2-Yl)Methanamine Dihydrochloride
CAS No.	1251953-03-3
Molecular Formula	C6H8BrCl2N2
Molecular Weight	256.95 g/mol
Synonyms	2-(Aminomethyl)-5-bromopyridine dihydrochloride; (5-Bromo-2-pyridinyl)methanamine dihydrochloride; 5-Bromo-2-pyridinemethanamine dihydrochloride; 2-Aminomethyl-5-bromopyridine dihydrochloride; 5-Bromopyridine-2-methanamine dihydrochloride; 5-Bromo-2-(aminomethyl)pyridine dihydrochloride; 5-Bromo-2-picolylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (5-Bromopyridin-2-Yl)Methanamine Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.