Description

Methyl 5-Chloro-1-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyridine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its role in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), especially those targeting specific biological pathways.
• Medicinal Chemistry R&D: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Biochemical Research: Employed in biochemical assays and as a tool compound for investigating enzyme inhibition or receptor binding.
• Academic Research: Used in university and institutional laboratories for advanced synthetic organic chemistry and heterocyclic compound research.

Basic Information

Product Name	Methyl 5-Chloro-1-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate
CAS No.	1251924-26-1
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.66 g/mol
Synonyms	5-Chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester; Methyl 5-chloro-1-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-2-carboxylic acid, 5-chloro-1-methyl-, methyl ester; 1251924-26-1; 5-Chloro-1-methyl-pyrrolo[3,2-b]pyridine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Chloro-1-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical intermediate applications, ensuring reliable supply and traceability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Impurity (HPLC)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.