Description

5-Bromo-3,4-Dihydro-1H-[2,7]Naphthyridine-2-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex heterocyclic scaffolds. It is primarily utilized by pharmaceutical and biotechnology companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential therapeutic agents, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of complex naphthyridine-based heterocycles for various chemical and biological applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Employed in university and institutional laboratories for the study of novel synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-3,4-Dihydro-1H-[2,7]Naphthyridine-2-Carboxylic Acid tert-Butyl Ester
CAS No.	1251012-16-4
Molecular Formula	C13H15BrN2O2
Molecular Weight	311.18 g/mol
Synonyms	tert-Butyl 5-bromo-3,4-dihydro-1H-[2,7]naphthyridine-2-carboxylate; 5-Bromo-1,2,3,4-tetrahydro-[2,7]naphthyridine-2-carboxylic acid tert-butyl ester; 5-Bromo-3,4-dihydro-2H-[2,7]naphthyridine-2-carboxylic acid 1,1-dimethylethyl ester; 1251012-16-4; 5-Bromo-3,4-dihydro-1H-[2,7]naphthyridine-2-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 5-Bromo-3,4-Dihydro-1H-[2,7]Naphthyridine-2-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.