Description

trans-tert-Butylhexahydro-2H-Pyrido[4,3-B][1,4]Oxazine-6(7H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of sophisticated active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and other therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in process development and scale-up of novel drug candidates.

Application

• Key Intermediate in API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex drug molecules.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the discovery and optimization of new therapeutic compounds, especially those targeting neurological pathways.
• Process Chemistry & Scale-Up: Employed in the development of robust and scalable manufacturing routes for clinical and commercial drug production.
• Contract Manufacturing Organizations (CMOs): Supplied to CMOs producing APIs for pharmaceutical clients under GMP guidelines.
• Academic & Institutional Research: Utilized in chemical biology and pharmacology studies investigating new mechanisms of action.

Basic Information

Product Name	trans-tert-Butylhexahydro-2H-Pyrido[4,3-B][1,4]Oxazine-6(7H)-Carboxylate
CAS No.	1251009-06-9
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	trans-tert-Butyl 1,2,3,4,6,7,8,8a-Octahydro-2H-Pyrido[4,3-b][1,4]oxazine-6-carboxylate; (6R,8aS)-tert-Butyl Hexahydro-2H-pyrido[4,3-b][1,4]oxazine-6-carboxylate; tert-Butyl (6R,8aS)-octahydro-2H-pyrido[4,3-b][1,4]oxazine-6-carboxylate; trans-tert-Butyl Octahydro-2H-pyrido[4,3-b][1,4]oxazine-6-carboxylate; BOC-Protected Pyridooxazine Intermediate; 1251009-06-9
EINECS	Contact for details

Quality Control

Our trans-tert-Butylhexahydro-2H-Pyrido[4,3-B][1,4]Oxazine-6(7H)-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.