Description

cis-tert-Butyl-Octahydropyrido[4,3-F][1,4]Oxazepine-8(2H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of critical importance for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on developing new therapeutic agents, particularly within the central nervous system (CNS) and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the development and scale-up production of Active Pharmaceutical Ingredients (APIs), especially those targeting neurological receptors.
• Process Chemistry Development: Serves as a key material for developing and optimizing robust, scalable synthetic routes in process R&D.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control testing.
• Academic & Institutional Research: Used in university and institutional labs for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	cis-tert-Butyl-Octahydropyrido[4,3-F][1,4]Oxazepine-8(2H)-Carboxylate
CAS No.	1251003-51-6
Molecular Formula	C15H26N2O3
Molecular Weight	282.38 g/mol
Synonyms	tert-Butyl (3aS,7aR)-octahydro-1H-pyrido[4,3-f][1,4]oxazepine-8(2H)-carboxylate; (3aS,7aR)-tert-Butyl octahydro-1H-pyrido[4,3-f][1,4]oxazepine-8(2H)-carboxylate; cis-8-(tert-Butoxycarbonyl)-2,3,3a,4,5,7,7a,8-octahydro-1H-pyrido[4,3-f][1,4]oxazepine; BOC-Protected Octahydropyridooxazepine; CAS 1251003-51-6
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl-Octahydropyrido[4,3-F][1,4]Oxazepine-8(2H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect against moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.