Description

Racemic-(2R,3As,7Ar)-1-Benzyl 5-tert-Butyl 2-(Hydroxymethyl)Hexahydro-1H-Pyrrolo[3,2-C]Pyridine-1,5(6H)-Dicarboxylate is a sophisticated chiral pyrrolopyridine derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its complex, functionalized bicyclic structure makes it invaluable for constructing molecules with specific three-dimensional configurations, which is essential for developing new active pharmaceutical ingredients. This compound is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex therapeutic agents, particularly in neurological and oncological research.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis Building Block: Utilized in the construction of complex natural products and bioactive molecules requiring precise stereochemical control.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Catalyst and Ligand Development: Serves as a scaffold for developing new chiral catalysts or ligands used in enantioselective transformations.
• Academic and Industrial R&D: Used in research laboratories for exploring new synthetic methodologies and chemical biology.

Basic Information

Product Name	Racemic-(2R,3As,7Ar)-1-Benzyl 5-tert-Butyl 2-(Hydroxymethyl)Hexahydro-1H-Pyrrolo[3,2-C]Pyridine-1,5(6H)-Dicarboxylate
CAS No.	1250993-22-6
Molecular Formula	C22H30N2O5
Molecular Weight	402.49 g/mol
Synonyms	1-Benzyl 5-tert-butyl 2-(hydroxymethyl)hexahydro-1H-pyrrolo[3,2-c]pyridine-1,5-dicarboxylate; (2R,3aS,7aR)-rel-1,5(6H)-Dicarboxylic acid, 1-(phenylmethyl) 5-(1,1-dimethylethyl) 2-(hydroxymethyl)hexahydro-1H-pyrrolo[3,2-c]pyridine-; rac-(2R,3aS,7aR)-1-Benzyl 5-tert-butyl 2-(hydroxymethyl)hexahydro-1H-pyrrolo[3,2-c]pyridine-1,5(6H)-dicarboxylate; Benzyl tert-butyl 2-(hydroxymethyl)hexahydro-1H-pyrrolo[3,2-c]pyridine-1,5-dicarboxylate; Chiral Pyrrolopyridine Derivative; Bicyclic Proline Derivative
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, NMR for structural confirmation, and MS for identity verification. We provide detailed Certificates of Analysis (COA) with each shipment, ensuring full traceability and compliance with the stringent requirements of pharmaceutical development and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; ensure the container is kept sealed to prevent contamination or degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Racemic mixture
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.