Description

3-Amino-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridin-2-one is a high-value, fluorinated heterocyclic building block with significant potential in advanced organic synthesis. Its core value lies in the unique combination of a reactive amino-dihydropyridinone scaffold and a metabolically stable trifluoroethyl group, enabling the development of novel compounds with enhanced properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients, particularly in medicinal chemistry programs targeting enzyme inhibition.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, or insecticides, where the trifluoromethyl group can improve lipophilicity and metabolic stability.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological pathways and protein function.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or ligands for catalysis that incorporate fluorine for specific performance characteristics.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis organizations (CSOs) serving the life sciences sector.

Basic Information

Product Name	3-Amino-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridin-2-one
CAS No.	1250672-75-3
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	3-Amino-1-(2,2,2-trifluoroethyl)-2(1H)-pyridinone; 3-Amino-1-(2,2,2-trifluoroethyl)-1,2-dihydro-2-pyridone; 1-(2,2,2-Trifluoroethyl)-3-amino-1,2-dihydropyridin-2-one; 3-Amino-1-(trifluoroethyl)dihydropyridin-2-one; CAS 1250672-75-3; 2(1H)-Pyridinone, 3-amino-1-(2,2,2-trifluoroethyl)-
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-1-(2,2,2-trifluoroethyl)-1,2-dihydropyridin-2-one is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storage under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.