Description

2-Amino-5-(2,5-Difluorophenyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine core substituted with amino and difluorophenyl groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, particularly in areas such as oncology and kinase inhibition.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, especially kinase inhibitors.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides.
• Material Science: Potential building block for advanced organic electronic materials and ligands for catalysis.

Basic Information

Product Name	2-Amino-5-(2,5-Difluorophenyl)Pyridine
CAS No.	1249608-12-5
Molecular Formula	C11H8F2N2
Molecular Weight	206.19 g/mol
Synonyms	5-(2,5-Difluorophenyl)pyridin-2-amine; 2-Pyridinamine, 5-(2,5-difluorophenyl)-; 2-Amino-5-(2,5-difluorophenyl)pyridine; 1249608-12-5; 5-(2,5-Difluorophenyl)-2-aminopyridine; 2-Amino-5-(2,5-difluorophenyl)pyridine; 5-(2,5-Difluorophenyl)-2-pyridinamine
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(2,5-Difluorophenyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.