Description

2-[(1-Methylpiperidin-4-Yl)Oxy]Pyridin-4-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure combining pyridine and piperidine motifs. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is essential for medicinal chemistry teams in pharmaceutical R&D and fine chemical manufacturers developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: Employed in pharmacological assays to study receptor interactions and enzyme inhibition.
• Fine Chemical Manufacturing: Supplied to contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs) for custom synthesis projects.

Basic Information

Product Name	2-[(1-Methylpiperidin-4-Yl)Oxy]Pyridin-4-Amine
CAS No.	1249316-39-9
Molecular Formula	C11H17N3O
Molecular Weight	207.27 g/mol
Synonyms	4-Amino-2-[(1-methyl-4-piperidinyl)oxy]pyridine; 2-((1-Methylpiperidin-4-yl)oxy)pyridin-4-amine; 4-Pyridinamine, 2-[(1-methyl-4-piperidinyl)oxy]-; 2-(1-Methylpiperidin-4-yloxy)pyridin-4-ylamine; 2-(N-Methyl-4-piperidyloxy)-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 2-[(1-Methylpiperidin-4-Yl)Oxy]Pyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.