Description

1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-3-Amine is a high-purity, advanced pharmaceutical intermediate featuring a bromopyridine and sulfonamide-linked pyrrolidine scaffold. This compound is valued for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Used in the research and construction of potential kinase inhibitors due to the privileged bromopyridine structure.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study enzyme function and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.
• Agrochemical Research: Potential intermediate in the discovery of new active ingredients for crop protection products.
• Material Science: Can be utilized in the synthesis of specialized ligands for catalysts or functional materials.

Basic Information

Product Name	1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-3-Amine
CAS No.	1247942-01-3
Molecular Formula	C9H12BrN3O2S
Molecular Weight	306.18 g/mol
Synonyms	3-Amino-1-[(5-bromo-3-pyridinyl)sulfonyl]pyrrolidine; 1-[(5-Bromopyridin-3-yl)sulfonyl]pyrrolidin-3-amine; Pyrrolidin-3-amine, 1-[(5-bromo-3-pyridinyl)sulfonyl]-; 5-Bromo-3-(3-aminopyrrolidine-1-sulfonyl)pyridine; 1-(5-Bromo-3-pyridinesulfonyl)pyrrolidin-3-amine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Ylsulfonyl)Pyrrolidin-3-Amine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for advanced intermediate production where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.