Description

2-Amino-2-(6-Chloropyridin-3-Yl)Acetic Acid Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a CAS number of 1246548-77-5. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a key chiral building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to develop novel therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and commercial synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides, leveraging the chloropyridine moiety for biological activity.
• Chemical Research & Development: Used in academic and industrial laboratories for method development, catalysis studies, and exploring new reaction pathways in organic synthesis.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of target molecules, ensuring robust and cost-effective production routes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	2-Amino-2-(6-Chloropyridin-3-Yl)Acetic Acid Hydrochloride
CAS No.	1246548-77-5
Molecular Formula	C7H8Cl2N2O2
Molecular Weight	223.06 g/mol
Synonyms	(6-Chloro-3-pyridinyl)glycine hydrochloride; 2-Amino-2-(6-chloro-3-pyridinyl)acetic acid hydrochloride; 2-Amino-2-(6-chloropyridin-3-yl)ethanoic acid hydrochloride; 6-Chloro-3-pyridylglycine HCl; (6-Chloro-3-pyridyl)glycine hydrochloride; 2-Amino-2-(6-chloro-3-pyridyl)acetic acid HCl; α-Amino-(6-chloro-3-pyridyl)acetic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(6-Chloropyridin-3-Yl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and internal quality standards. We support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.