Description

7-Methyl-1,2,3,4-Tetrahydro-[1,8]Naphthyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in R&D laboratories.
• API Synthesis: Used in the multi-step manufacturing process of final Active Pharmaceutical Ingredients, where high purity and consistent quality are paramount.
• Bioconjugation & Probe Development: Its carboxylic acid functional group makes it suitable for conjugation chemistry in the development of biochemical probes and diagnostic agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	7-Methyl-1,2,3,4-Tetrahydro-[1,8]Naphthyridine-2-Carboxylic Acid
CAS No.	1246548-23-1
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	7-Methyl-1,2,3,4-tetrahydro-1,8-naphthyridine-2-carboxylic acid; 2-Carboxy-7-methyl-1,2,3,4-tetrahydro-1,8-naphthyridine; 7-Methyl-3,4-dihydro-1,8-naphthyridine-2(1H)-carboxylic acid; 7-Methyl-1,2,3,4-tetrahydro[1,8]naphthyridine-2-carboxylic acid; 1246548-23-1; 7-Methyl-THN-2-COOH; 7-Me-THN-2-COOH
EINECS	Contact for details

Quality Control

Our production of 7-Methyl-1,2,3,4-Tetrahydro-[1,8]Naphthyridine-2-Carboxylic Acid adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.