Description

4-(5-Aminopyridin-3-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique bifunctional aromatic structure. This compound matters as a critical building block for synthesizing novel, complex molecules, particularly in drug discovery and development pipelines. It is primarily needed by research institutions and pharmaceutical companies engaged in creating new active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors for oncology and inflammatory diseases.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct sophisticated heterocyclic systems due to its reactive amine and nitrile groups.
• Agrochemical Research: Serves as a structural component in the development of new pesticides and herbicides.
• Material Science: Investigated as a monomer or precursor for functional polymers and organic electronic materials.
• Chemical Biology Probe Development: Used to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	4-(5-Aminopyridin-3-Yl)Benzonitrile
CAS No.	1246350-47-9
Molecular Formula	C12H9N3
Molecular Weight	195.22 g/mol
Synonyms	3-(4-Cyanophenyl)-5-aminopyridine; 5-Amino-3-(4-cyanophenyl)pyridine; 4-(5-Amino-3-pyridinyl)benzonitrile; Benzonitrile, 4-(5-amino-3-pyridinyl)-; [1,1'-Biphenyl]-4-carbonitrile, 3'-amino-
EINECS	Contact for details

Quality Control

Our 4-(5-Aminopyridin-3-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.