Description

(25R)-Cholest-5-En-26-Oic Acid, 3,7-Hydroxy is a high-purity, steroidal acid derivative characterized by its specific hydroxylation pattern at the 3 and 7 positions. This compound serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical companies, biotechnology research labs, and academic institutions focused on metabolic pathways, receptor studies, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of cholesterol metabolism, liver X receptor (LXR) pathways, and bile acid signaling.
• Analytical Standard: Serves as a high-purity calibration standard for HPLC, LC-MS, and other analytical methods in quality control laboratories.
• Nutraceutical Development: Investigated for potential applications in the development of specialized dietary supplements targeting metabolic health.
• Academic & Contract Research: Essential for basic research in organic chemistry, medicinal chemistry, and pharmacology within universities and CROs.

Basic Information

Product Name	(25R)-Cholest-5-En-26-Oic Acid, 3,7-Hydroxy
CAS No.	1246298-66-7
Molecular Formula	C₂₇H₄₄O₄
Molecular Weight	432.64 g/mol
Synonyms	3β,7α-Dihydroxy-5-cholesten-26-oic acid; (25R)-3β,7α-Dihydroxy-5-cholesten-26-oic Acid; 3,7-Dihydroxycholest-5-en-26-oic Acid; 7α-Hydroxy-3β-hydroxycholest-5-en-26-oic Acid; Cholest-5-ene-3,7-diol-26-oic acid; 26-Carboxy-3,7-dihydroxycholest-5-ene; A potential bile acid intermediate; 5-Cholestene-3,7,26-triol, 26-carboxylic acid (related form)
EINECS	Contact for details

Quality Control

Our (25R)-Cholest-5-En-26-Oic Acid, 3,7-Hydroxy is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and impurities. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.