Description

tert-Butyl (1-Pivaloyl-2,3-Dihydro-1H-Pyrido-[2,3-B][1,4]Oxazin-6-Yl)Carbamate is a sophisticated heterocyclic organic compound featuring a fused pyrido-oxazine core with a pivaloyl and a Boc-protecting group. This compound matters as a key advanced intermediate in the synthesis of complex pharmaceutical molecules, offering a versatile scaffold for medicinal chemistry. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The structural motif suggests potential application in the design and synthesis of protease inhibitors for various therapeutic targets.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clinical trials.
• Academic Research: Employed in university and institutional labs for methodological development in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	tert-Butyl (1-Pivaloyl-2,3-Dihydro-1H-Pyrido-[2,3-B][1,4]Oxazin-6-Yl)Carbamate
CAS No.	1246088-45-8
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	tert-Butyl N-(1-pivaloyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)carbamate; 1H-Pyrido[2,3-b][1,4]oxazine-6-carboxamide, N-(1,1-dimethylethoxy)carbonyl-2,3-dihydro-1-(2,2-dimethyl-1-oxopropoxy)-; 6-((tert-Butoxycarbonyl)amino)-1-pivaloyl-1,2,3,4-tetrahydropyrido[2,3-b][1,4]oxazine; Boc-Protected 1-Pivaloyl-1,2,3,4-tetrahydropyrido[2,3-b][1,4]oxazin-6-amine; 1246088-45-8; tert-Butyl (1-Pivaloyl-1,2,3,4-tetrahydropyrido[2,3-b][1,4]oxazin-6-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (1-Pivaloyl-2,3-Dihydro-1H-Pyrido-[2,3-B][1,4]Oxazin-6-Yl)Carbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.