Description

Ethyl 1-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1245808-56-3. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), offering significant value in modern drug discovery and development pipelines. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies focused on developing innovative therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for potential drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• API Synthesis: Serves as a core scaffold in the multi-step production of investigational new drugs, particularly in oncology and central nervous system (CNS) research.
• Contract Manufacturing: Supplied to CDMOs for custom synthesis projects under cGMP or research-grade conditions.
• Biochemical Research: Utilized as a reference standard or tool compound in biochemical assays and pharmacological studies.

Basic Information

Product Name	Ethyl 1-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate
CAS No.	1245808-56-3
Molecular Formula	C11H11N3O3
Molecular Weight	233.22 g/mol
Synonyms	Ethyl 1-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6,7-dihydro-1-methyl-6-oxo-, ethyl ester; Ethyl 1-methyl-6-oxo-1,6-dihydro-7H-pyrazolo[3,4-b]pyridine-4-carboxylate; 1245808-56-3; Ethyl 1-methyl-6-oxo-7H-pyrazolo[3,4-b]pyridine-4-carboxylate; 1-Methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use or produced under cGMP guidelines for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.