Description

3-(5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Propanoic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile pyrazolopyridine scaffold for creating targeted drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Serves as a core scaffold for the research and production of small molecule kinase inhibitors, a major class of oncology and anti-inflammatory drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Biochemical Tool Compound: Employed in the development of probes for studying biological mechanisms and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	3-(5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Propanoic Acid
CAS No.	1245807-66-2
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	3-(5-Methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)propanoic acid; 1H-Pyrazolo[3,4-b]pyridine-1-propanoic acid, 5-methyl-; 5-Methyl-1H-pyrazolo[3,4-b]pyridine-1-propanoic acid; 3-(5-Methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)propionic acid; 1245807-66-2; 5-Methyl-1-(2-carboxyethyl)-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 3-(5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.