Description

5-Chloro-1-p-Tolyl-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester is a high-purity pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling precise molecular construction. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its heterocyclic core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in multi-step synthetic routes for constructing complex molecular architectures in final API production.
• Material Science Research: Potential intermediate for developing specialty polymers or organic electronic materials with specific functional properties.

Basic Information

Product Name	5-Chloro-1-p-Tolyl-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester
CAS No.	1245258-69-8
Molecular Formula	C14H15ClN2O2
Molecular Weight	278.73 g/mol
Synonyms	Ethyl 5-Chloro-1-(4-methylphenyl)-1H-pyrazole-4-carboxylate; 5-Chloro-1-(4-methylphenyl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester; 1H-Pyrazole-4-carboxylic acid, 5-chloro-1-(4-methylphenyl)-, ethyl ester; 5-Chloro-1-p-tolylpyrazole-4-carboxylic acid ethyl ester; 5-Chloro-1-(p-tolyl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester; 1245258-69-8; Ethyl 5-chloro-1-p-tolyl-1H-pyrazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-p-Tolyl-1H-Pyrazole-4-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical and agrochemical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.