Description

n-(5-Bromo-2-Methylpyridin-4-Yl)Acetamide is a high-purity brominated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and acetamide functionalities into target structures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	n-(5-Bromo-2-Methylpyridin-4-Yl)Acetamide
CAS No.	1244949-22-1
Molecular Formula	C8H9BrN2O
Molecular Weight	229.08 g/mol
Synonyms	5-Bromo-2-methyl-4-acetamidopyridine; 4-Acetamido-5-bromo-2-methylpyridine; N-(5-Bromo-2-methyl-4-pyridinyl)acetamide; Acetamide, N-(5-bromo-2-methyl-4-pyridinyl)-; 1244949-22-1; 5-Bromo-2-methylpyridin-4-amine, N-acetyl derivative
EINECS	Contact for details

Quality Control

Our n-(5-Bromo-2-Methylpyridin-4-Yl)Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, supporting development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.