Description

(5-Chloro-Thiazolo[5,4-B]Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on oncology, antiviral, and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly in heterocyclic chemistry.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Oncology Drug Development: Serves as a scaffold for creating potential kinase inhibitors and other targeted cancer therapies.
• Antiviral Agent Synthesis: Employed in the research and development of new antiviral compounds.
• Chemical Biology Probes: Used to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.

Basic Information

Product Name	(5-Chloro-Thiazolo[5,4-B]Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1244059-48-0
Molecular Formula	C11H12ClN3O2S
Molecular Weight	285.75 g/mol
Synonyms	tert-Butyl (5-chlorothiazolo[5,4-b]pyridin-2-yl)carbamate; 5-Chloro-2-(((tert-butoxy)carbonyl)amino)thiazolo[5,4-b]pyridine; N-Boc-5-chlorothiazolo[5,4-b]pyridin-2-amine; (5-Chloro-thiazolo[5,4-b]pyridin-2-yl)-carbamic acid tert-butyl ester; BOC-5-Chloro-Thiazolo[5,4-B]Pyridin-2-Amine; 1244059-48-0; tert-Butyl N-(5-chlorothiazolo[5,4-b]pyridin-2-yl)carbamate
EINECS	Contact for details

Quality Control

Our (5-Chloro-Thiazolo[5,4-B]Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements, supporting regulatory filings from R&D through to commercial production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.