Description

5-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylic Acid is a high-value heterocyclic building block and carboxylic acid derivative, primarily utilized in advanced pharmaceutical research and development. Its core value lies in its role as a critical synthetic intermediate for constructing complex molecules, particularly in the creation of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who require precise, high-purity intermediates for lead optimization and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and other targeted therapy research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its fused pyrrolopyridine scaffold.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: Fundamental reagent for synthetic organic chemistry research in universities and contract research organizations (CROs).
• Custom Synthesis: Starting material for the custom manufacturing of complex, proprietary molecules for client-specific applications.

Basic Information

Product Name	5-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylic Acid
CAS No.	1242427-34-4
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid; 2-Carboxy-5-methyl-1H-pyrrolo[3,2-b]pyridine; 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid; 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid (CAS 1242427-34-4); 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid, 1242427-34-4; 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid (9CI); 5-Methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid, 1242427-34-4
EINECS	Contact for details

Quality Control

Our 5-Methyl-1H-Pyrrolo[3,2-B]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and other high-purity applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.