Description

tert-Butyl 6-(Dimethylamino)Pyridin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a protected carbamate group on a functionalized pyridine scaffold. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to build novel nitrogen-containing heterocycles with specific steric and electronic properties.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of targeted kinase inhibitors and other small molecule therapeutics.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization campaigns.
• Process Chemistry: Serves as a crucial starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Academia & Institutional Research: Employed in organic synthesis laboratories for developing new methodologies involving protected amino-pyridine derivatives.
• Custom Synthesis: A substrate for the preparation of more complex, custom-designed molecules for specialized client projects.

Basic Information

Product Name	tert-Butyl 6-(Dimethylamino)Pyridin-3-Ylcarbamate
CAS No.	1242333-49-8
Molecular Formula	C12H19N3O2
Molecular Weight	237.30 g/mol
Synonyms	tert-Butyl (6-(dimethylamino)pyridin-3-yl)carbamate; 3-Pyridinecarboxamide, 6-(dimethylamino)-N-[(1,1-dimethylethoxy)carbonyl]-; 6-(Dimethylamino)pyridin-3-amine, N-Boc-protected; Boc-6-(Dimethylamino)-3-aminopyridine; N-Boc-6-(Dimethylamino)pyridin-3-amine; tert-Butyl N-[6-(dimethylamino)pyridin-3-yl]carbamate; 1242333-49-8
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-(Dimethylamino)Pyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.