Description

3-Amino-2-Chloropyridin-4-Ol is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures with precision. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting components.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	3-Amino-2-Chloropyridin-4-Ol
CAS No.	1242251-52-0
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	2-Chloro-3-amino-4-hydroxypyridine; 4-Hydroxy-2-chloro-3-aminopyridine; 3-Amino-2-chloro-4-pyridinol; 2-Chloro-3-amino-4-pyridone; 3-Amino-2-chloro-4(1H)-pyridinone; 2-Chloro-3-amino-4(1H)-pyridone; 3-Amino-2-chloro-4-hydroxypyridine
EINECS	Contact for details

Quality Control

Our 3-Amino-2-Chloropyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.