Description

Enzalutamide CAS NO 1242137-17-2 is a potent, second-generation nonsteroidal antiandrogen used in the treatment of metastatic castration-resistant prostate cancer (mCRPC). It functions as a selective androgen receptor inhibitor, effectively blocking androgen receptor signaling and nuclear translocation. This active pharmaceutical ingredient (API) is critical for pharmaceutical manufacturers and research institutions developing advanced oncology therapeutics.

Application

• Primary Active Pharmaceutical Ingredient (API) in the formulation of oral anti-cancer medications for prostate cancer.
• Key intermediate in advanced pharmaceutical research and development of novel androgen receptor-targeting therapies.
• Reference standard for quality control and analytical testing in pharmaceutical manufacturing and regulatory compliance.
• Biochemical research tool for studying androgen receptor pathways, mechanisms of resistance, and drug discovery in oncology.
• Used in the development of combination therapies and next-generation treatments for hormone-sensitive cancers.

Basic Information

Product Name	Enzalutamide
CAS No.	1242137-17-2
Molecular Formula	C21H16F4N4O2S
Molecular Weight	464.44 g/mol
Synonyms	MDV3100; Xtandi (trade name); 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl]-2-fluoro-N-methylbenzamide; N-(4-Cyano-3-(trifluoromethyl)phenyl)-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methylpropanamide (alternative IUPAC); ASP9785; Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methyl-
EINECS	Contact for details

Quality Control

Our Enzalutamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the highest standards for pharmaceutical use, including identity, purity, and impurity profile verification. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications and supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.