Description

tert-Butyl (5-Hydroxypyridin-2-Yl)Methylcarbamate is a specialized carbamate-protected pyridine derivative, serving as a crucial pharmaceutical intermediate and organic building block. Its value lies in its functional groups, which allow for selective deprotection and further chemical transformations under mild conditions. This compound is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for developing active pharmaceutical ingredients (APIs) and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Reagent: Used in medicinal chemistry for the protection of amine groups and the construction of heterocyclic scaffolds.
• Agrochemical Research: Intermediate in the development of new pesticides and herbicides with pyridine-based structures.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Academic & Industrial R&D: Serves as a versatile starting material for novel compound libraries in high-throughput screening programs.

Basic Information

Product Name	tert-Butyl (5-Hydroxypyridin-2-Yl)Methylcarbamate
CAS No.	1240620-37-4
Molecular Formula	C12H18N2O3
Molecular Weight	238.28 g/mol
Synonyms	tert-Butyl N-[(5-hydroxypyridin-2-yl)methyl]carbamate; 2-[[(tert-Butoxycarbonyl)amino]methyl]-5-hydroxypyridine; 5-Hydroxy-2-[(Boc-amino)methyl]pyridine; Boc-AMHP; (5-Hydroxy-2-pyridylmethyl)carbamic acid tert-butyl ester; N-Boc-2-(aminomethyl)-5-hydroxypyridine; tert-Butyl (5-hydroxy-2-pyridinylmethyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Hydroxypyridin-2-Yl)Methylcarbamate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all specified parameters. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.