Description

3-Fluoro-5-(Pentafluorosulfur)Benzoyl Chloride is a highly reactive and versatile fluorinated aromatic building block. This compound matters for its unique combination of fluorine and sulfur pentafluoride groups, which are critical for modulating the electronic properties, metabolic stability, and lipophilicity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, particularly in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, especially in areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and SF5 groups enhance biological activity and environmental persistence.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated compounds used in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) due to its ability to influence dielectric anisotropy and stability.
• Polymer Modification: Employed to introduce fluorinated benzoyl groups into polymer chains, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Organic Synthesis & Catalysis Research: Acts as a specialized reagent in academic and industrial research for constructing complex, fluorinated aromatic structures and exploring new catalytic methodologies.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a precursor for synthesizing fluorine-18 labeled tracers for medical imaging, leveraging its aromatic fluorine atom.

Basic Information

Product Name	3-Fluoro-5-(Pentafluorosulfur)Benzoyl Chloride
CAS No.	1240256-92-1
Molecular Formula	C7H2ClF6OS
Molecular Weight	276.60 g/mol
Synonyms	3-Fluoro-5-(pentafluoro-λ6-sulfanyl)benzoyl chloride; 5-(Pentafluorosulfanyl)-3-fluorobenzoyl chloride; Benzoyl chloride, 3-fluoro-5-(pentafluorosulfanyl)-; 3-Fluoro-5-SF5-benzoyl chloride; SF5-Fluorobenzoyl chloride; 3-Fluoro-5-(SF5)benzoyl chloride; 3-Fluoro-5-(pentafluorosulfuryl)benzoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Pentafluorosulfur)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.