Description

2-Fluoro-4-(Pentafluorosulfur)Benzoylchloride is a high-value, multi-functional fluorinated building block essential for advanced chemical synthesis. Its unique structure, featuring both a reactive acid chloride group and a pentafluorosulfur substituent, makes it a critical intermediate for introducing specific fluorinated motifs into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides where the pentafluorosulfur group can improve biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & Electronic Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), where it can modify dielectric properties and thermal stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing their chemical resistance, surface properties, and durability for specialty coatings and high-performance materials.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and other coupling reactions to construct complex, fluorinated aromatic systems in medicinal and materials chemistry research.

Basic Information

Item	Detail
Product Name	2-Fluoro-4-(Pentafluorosulfur)Benzoylchloride
CAS No.	1240256-85-2
Molecular Formula	C7HF6ClOS
Molecular Weight	282.59 g/mol
Synonyms	4-(Pentafluoro-λ6-sulfanyl)-2-fluorobenzoyl chloride; 2-Fluoro-4-(pentafluorosulfanyl)benzoyl chloride; 2-Fluoro-4-(SF5)benzoyl chloride; SF5-Benzoyl chloride derivative; Benzoyl chloride, 2-fluoro-4-(pentafluorosulfanyl)-; 1240256-85-2
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-(Pentafluorosulfur)Benzoylchloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and GC-MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) when not in use. Keep away from strong bases and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.