Description

6-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyridin-2-Ylamine is a high-value heterocyclic building block featuring a fused triazolopyridine core with a reactive amine group and a trifluoromethyl substituent. This compound matters for its unique combination of structural motifs, which are highly sought after in modern pharmaceutical and agrochemical research for modulating the physicochemical properties and biological activity of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Active Ingredient Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for constructing complex organic frameworks, ligands for catalysis, and specialty polymers with tailored electronic properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes, enzyme inhibitors, and tool compounds in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specialized heterocycle.

Basic Information

Product Name	6-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyridin-2-Ylamine
CAS No.	1239648-22-6
Molecular Formula	C7H4F3N5
Molecular Weight	215.14 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridine; 6-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 6-Trifluoromethyl-1,2,4-triazolo[1,5-a]pyridin-2-amine; 1239648-22-6; 6-Trifluoromethyl-[1,2,4]triazolo[1,5-A]pyridin-2-amine; 2-Amino-6-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridine
EINECS	Contact for details

Quality Control

Our 6-Trifluoromethyl-[1,2,4]Triazolo[1,5-A]Pyridin-2-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.