Description

tert-Butyl 2-Chloro-4-Formylpyridin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its pyridine core with chloro, formyl, and carbamate functional groups. This compound is critical for its role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel pesticides and herbicides due to its bioactive pyridine scaffold.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and CROs (Contract Research Organizations).
• Process Chemistry: Employed in route scouting and optimization for scalable API manufacturing processes.

Basic Information

Item	Details
Product Name	tert-Butyl 2-Chloro-4-Formylpyridin-3-Ylcarbamate
CAS No.	1238324-73-6
Molecular Formula	C11H13ClN2O3
Molecular Weight	256.69 g/mol
Synonyms	tert-Butyl (2-chloro-4-formylpyridin-3-yl)carbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-chloro-4-pyridinecarboxaldehyde; 2-Chloro-4-formylpyridin-3-yl-carbamic acid tert-butyl ester; tert-Butyl N-(2-chloro-4-formyl-3-pyridyl)carbamate; BOC-2-Chloro-4-formyl-3-aminopyridine; 1238324-73-6
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chloro-4-Formylpyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.