Description

1-(2-Chloro-3-Fluoropyridin-4-Yl)Ethanone is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which enables the introduction of key functional groups for creating complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, catalysts, and functional polymers.
• Chemical Biology: Employed as a probe or labeling reagent in medicinal chemistry and biochemical studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for bespoke chemical manufacturing.

Basic Information

Product Name	1-(2-Chloro-3-Fluoropyridin-4-Yl)Ethanone
CAS No.	1236770-00-5
Molecular Formula	C7H5ClFNO
Molecular Weight	173.57 g/mol
Synonyms	2-Chloro-3-fluoro-4-acetylpyridine; 4-Acetyl-2-chloro-3-fluoropyridine; 1-(2-Chloro-3-fluoro-4-pyridinyl)ethanone; Ethanone, 1-(2-chloro-3-fluoro-4-pyridinyl)-; 2-Chloro-3-fluoro-4-pyridyl methyl ketone; 2-Chloro-3-fluoropyridin-4-yl methyl ketone; 4-Acetyl-2-chloro-3-fluoropyridine
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-3-Fluoropyridin-4-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.