Description

Methyl 4-Fluoro-2-{1H-Pyrrolo[2,3-B]Pyridin-5-Yloxy}Benzoate is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic benzoate structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, especially in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Biochemical Tool Compound: Serves as a precursor for developing labeled probes or active pharmaceutical ingredients (APIs) for biological testing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Methyl 4-Fluoro-2-{1H-Pyrrolo[2,3-B]Pyridin-5-Yloxy}Benzoate
CAS No.	1235865-75-4
Molecular Formula	C15H11FN2O3
Molecular Weight	286.26 g/mol
Synonyms	Methyl 4-fluoro-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)benzoate; 4-Fluoro-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)benzoic acid methyl ester; 5-((2-(Methoxycarbonyl)-5-fluorophenoxy)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-5-ol, 4-fluoro-2-(methoxycarbonyl)phenyl ether; CAS 1235865-75-4
EINECS	Contact for details

Quality Control

Our Methyl 4-Fluoro-2-{1H-Pyrrolo[2,3-B]Pyridin-5-Yloxy}Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.