Description

(2S)-[3,4-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Phenyl]-1,2-Propanediol is a high-purity, protected diol intermediate of significant importance in advanced organic synthesis. This compound is specifically designed to provide controlled reactivity and enhanced stability for sensitive multi-step chemical processes. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex active molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides and herbicides.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of novel chiral catalysts.
• Peptide & Natural Product Synthesis: Provides a protected phenolic diol functionality for constructing complex natural product analogs and peptide mimetics.
• Material Science Precursor: Employed in the research of specialty polymers and advanced organic electronic materials requiring specific stereochemistry.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(2S)-[3,4-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Phenyl]-1,2-Propanediol
CAS No.	1235828-10-0
Molecular Formula	C23H44O4Si2
Molecular Weight	440.77 g/mol
Synonyms	(2S)-1,2-Dihydroxy-3-[3,4-bis[(tert-butyldimethylsilyl)oxy]phenyl]propane; (S)-3,4-Bis-O-(tert-butyldimethylsilyl)-DOPA Diol; (S)-3,4-Bis-O-TBDMS-DOPA Diol; (2S)-3-[3,4-Bis[(tert-butyldimethylsilyl)oxy]phenyl]-1,2-propanediol; Protected L-DOPA Diol; TBDMS-protected Dihydroxyphenylalanine Diol Derivative
EINECS	Contact for details

Quality Control

Our (2S)-[3,4-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Phenyl]-1,2-Propanediol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and residual solvent analysis, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.