Description

2-(2,2-Dimethyl-Propionylamino)-Isonicotinic Acidmethyl Ester is a high-purity pharmaceutical intermediate and fine chemical building block. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and active pharmaceutical ingredient (API) development. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for its specific reactivity and structural features.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in research and development for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and herbicides.
• Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex heterocyclic compounds and fine chemicals.

Basic Information

Item	Detail
Product Name	2-(2,2-Dimethyl-Propionylamino)-Isonicotinic Acidmethyl Ester
CAS No.	1235666-16-6
Molecular Formula	C13H18N2O3
Molecular Weight	250.29 g/mol
Synonyms	2-(2,2-Dimethylpropanamido)isonicotinic acid methyl ester; Methyl 2-(pivalamido)isonicotinate; 2-Pivalamidoisonicotinic acid methyl ester; 2-(Pivaloylamino)isonicotinic acid methyl ester; 2-(2,2-Dimethylpropionylamino)isonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 2-[(2,2-dimethyl-1-oxopropyl)amino]-, methyl ester; Pivalic acid (2-methoxycarbonyl-4-pyridyl)amide
EINECS	Contact for details

Quality Control

Our 2-(2,2-Dimethyl-Propionylamino)-Isonicotinic Acidmethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.