Description

3-Iodo-2-Pyrrolidin-1-Ylpyridine is a specialized heterocyclic building block featuring a pyridine core substituted with iodine and a pyrrolidine group. This compound is of significant value in medicinal chemistry and pharmaceutical research as a key intermediate for the synthesis of novel drug candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to construct complex molecules for biological screening and optimization.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential therapeutic agents, particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated heterocyclic structure.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential intermediate in the synthesis of organic electronic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific custom synthesis projects.

Basic Information

Product Name	3-Iodo-2-Pyrrolidin-1-Ylpyridine
CAS No.	1235440-37-5
Molecular Formula	C9H11IN2
Molecular Weight	274.10 g/mol
Synonyms	2-(Pyrrolidin-1-yl)-3-iodopyridine; 3-Iodo-2-(1-pyrrolidinyl)pyridine; 3-Iodo-2-pyrrolidin-1-yl-pyridine; 3-Iodo-2-(pyrrolidin-1-yl)pyridine; Pyrrolidine, 1-(3-iodo-2-pyridinyl)-; 1-(3-Iodo-2-pyridinyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 3-Iodo-2-Pyrrolidin-1-Ylpyridine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.