Description

2-(2-Aminopyridin-4-Yl)-4-Chlorophenol is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes and diagnostic agents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP or research-grade conditions.

Basic Information

Product Name	2-(2-Aminopyridin-4-Yl)-4-Chlorophenol
CAS No.	1235406-61-7
Molecular Formula	C11H9ClN2O
Molecular Weight	220.66 g/mol
Synonyms	4-Chloro-2-(2-aminopyridin-4-yl)phenol; 2-(2-Amino-4-pyridinyl)-4-chlorophenol; 4-Chloro-2-(2-aminopyridin-4-yl)phenol; 2-Amino-4-(5-chloro-2-hydroxyphenyl)pyridine; 4-(5-Chloro-2-hydroxyphenyl)pyridin-2-amine; Phenol, 4-chloro-2-(2-amino-4-pyridinyl)-; 1235406-61-7
EINECS	Contact for details

Quality Control

Our 2-(2-Aminopyridin-4-Yl)-4-Chlorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We can supply material compliant with research-grade, technical-grade, or custom purity specifications to meet your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the original packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.