Description

4-Amino-5-Bromopicolinonitrile is a high-value brominated picolinonitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both amino and bromo substituents on the pyridine ring, makes it an essential building block for constructing complex heterocyclic systems and functional molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the research and development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	4-Amino-5-Bromopicolinonitrile
CAS No.	1234616-76-2
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo-4-aminopicolinonitrile; 4-Amino-5-bromo-2-cyanopyridine; 2-Cyano-4-amino-5-bromopyridine; 5-Bromo-4-amino-2-pyridinecarbonitrile; 4-Amino-5-bromopyridine-2-carbonitrile; 2-Pyridinecarbonitrile, 4-amino-5-bromo-; 4-Amino-5-bromo-2-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 4-Amino-5-Bromopicolinonitrile is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.