Description

Ethyl 2-(5-Iodopyridin-2-Yl)Acetate is a high-purity iodinated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its versatile reactivity, particularly in cross-coupling reactions and as a building block for complex heterocyclic systems. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Material Science: A building block for organic electronic materials and liquid crystals due to its aromatic and halogenated structure.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form biaryl structures.

Basic Information

Product Name	Ethyl 2-(5-Iodopyridin-2-Yl)Acetate
CAS No.	1234615-80-5
Molecular Formula	C9H10INO2
Molecular Weight	291.09 g/mol
Synonyms	Ethyl (5-iodopyridin-2-yl)acetate; 2-(5-Iodo-2-pyridinyl)acetic acid ethyl ester; Ethyl 2-(5-iodo-2-pyridinyl)acetate; Acetic acid, 2-(5-iodo-2-pyridinyl)-, ethyl ester; 5-Iodo-2-pyridineacetic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-(5-Iodopyridin-2-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications in GMP and research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.